Que Son Los Esteroides Anabolizantes Androgenicos

Content:
  • Anabolizante androgénico esteroideo
  • Esteroides Anabólicos Androgénicos by Laura Berroa on Prezi
  • SciELO - Scientific Electronic Library Online
  • Esteroides y Anabolizantes by Natalia Reyes on Prezi
  • Anabolizante androgénico esteroideo
  • 5) Anabolicos Esteroides Androgénicos (Entrenamiento Completo de Musculación)

    Anabolizante androgénico esteroideo

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    Esteroides Anabólicos Androgénicos by Laura Berroa on Prezi

    que son los esteroides anabolizantes androgenicos

    El abuso de los esteroides se ha difundido a tal extremo en el atletismo , que afecta el resultado de las competencias deportivas. Sin embargo, no existen evidencias concretas que indiquen que los esteroides anabolizantes incrementen la resistencia o la velocidad. La seguridad del uso de esteroides anabolizantes es dudosa. Los efectos de los tratamientos a largo plazo no han sido estudiados, ni tampoco los efectos de dosis extraordinariamente altas que usan algunos atletas, en especial los culturistas, que algunas veces utilizan dosis equivalentes a varios gramos semanales de metiltestosterona.

    Los varones pueden desarrollar ginecomastia , atrofia testicular y azoospermia. Testosterona — Testosterone is the primary male sex hormone and an anabolic steroid. In addition, testosterone is essential for health and well-being, insufficient levels of testosterone in men may lead to abnormalities including frailty and bone loss.

    Testosterone is also used as a medication to treat male hypogonadism, since testosterone levels gradually decrease as men age, synthetic testosterone is sometimes prescribed to older men to counteract this deficiency.

    Testosterone is a steroid from the class containing a keto. It is biosynthesized in several steps from cholesterol and is converted in the liver to inactive metabolites and it exerts its action through binding to and activation of the androgen receptor. In humans and most other vertebrates, testosterone is secreted primarily by the testicles of males and, to a lesser extent, small amounts are also secreted by the adrenal glands.

    On average, in males, levels of testosterone are about 7—8 times as great as in adult females. As the metabolic consumption of testosterone in males is greater, the production is about 20 times greater in men. Females are also sensitive to the hormone. In general, androgens such as testosterone promote protein synthesis and thus growth of tissues with androgen receptors, Testosterone can be described as having virilising and anabolic effects.

    Anabolic effects include growth of mass and strength, increased bone density and strength. Many of these fall into the category of secondary sex characteristics. Testosterone effects can also be classified by the age of usual occurrence, for postnatal effects in both males and females, these are mostly dependent on the levels and duration of circulating free testosterone.

    Effects before birth are divided into two categories, classified in relation to the stages of development, the first period occurs between 4 and 6 weeks of the gestation. There is also development of the gland and seminal vesicles. During the second trimester, androgen level is associated with gender formation and this period affects the femininization or masculinization of the fetus and can be a better predictor of feminine or masculine behaviours such as sex typed behaviour than an adults own levels.

    Early infancy androgen effects are the least understood, in the first weeks of life for male infants, testosterone levels rise. The levels remain in a range for a few months. Sustanon — Sustanon is a trade name owned by Organon Pharmaceuticals for oil-based injectable blends of esterized testosterone compounds. This smaller dose was usually for pediatric use,20 mg testosterone propionate 40 mg testosterone phenylpropionate 40 mg testosterone isocaproate Sustanon has not been produced since Esterization of the testosterone molecules provides for a release of testosterone from the injection depot into the blood plasma.

    Sustanon is the method of testosterone replacement in the UK as detailed in the British National Formulary. There was a shortage of Sustanon during late , due to licensing problems. This form of testosterone is a choice of anabolic steroid among bodybuilders. Boldenone itself has never been marketed, as a drug, it is used as boldenone undecylenate. The activity of boldenone is mainly anabolic, with a low androgenic potency, boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys.

    Boldenone was synthesized in an attempt to create a long-acting injectable methandrostenolone, boldenone acts similar to methandrostenolone with fewer adverse androgenic effects. Although commonly compared to nandrolone, boldenone lacks progesterone receptor interaction, boldenone is among the substances banned by Major League Baseball, as well as most other major athletic organizations.

    Abraham Almonte was suspended for 80 games before the season after testing positive for boldenone, stephan Bonnar and Josh Barnett, mixed martial arts fighters from the UFC and PRIDE Fighting Championships, have also tested positive for the banned substance. Justin Charles, a minor league baseball player with the Florida Marlins.

    Her horse Perfectly Poised was found to have traces of the banned substance boldenone in its system after finishing second at Canterbury in April , quinbolone, the cyclopentenyl enol ether of boldenone. Relative to testosterone, DHT is considerably more potent as an agonist of the androgen receptor. DHT has an affinity of 0. The terminal half-life of DHT in the body is longer than that of testosterone, a study of transdermal DHT and testosterone treatment reported terminal half-lives of 2.

    This genetic mutation can result in pseudohermaphroditism, the condition typically presents with underdeveloped male genitalia and prostate. Males with this condition are often raised as girls due to their lack of male genitalia. At the onset of puberty, although their DHT levels remain very low and their musculature develops like that of other male adults. After puberty, men with this condition have a deficiency of pubic and body hair.

    They also reportedly have no incidence of prostate cancer, unlike other androgens such as testosterone, DHT cannot be converted by the enzyme aromatase into an estrogen like estradiol.

    In the case of female androgenic alopecia, on the hand, the situation is more complex. Women with increased levels of DHT may develop symptoms of such as certain androgynous masculine secondary sex characteristics, including a deepened voice. In men, prostate growth and differentiation are highly dependent on androgens, especially DHT, both finasteride and dutasteride are approved for the treatment of BPH and androgenic alopecia.

    Dutasteride is three times more potent than finasteride in inhibiting the type II enzyme and times more potent than finasteride in inhibiting the type I form of the DHT-producing enzyme, both finasteride and dutasteride are potent inhibitors of the third isotype of the enzyme.

    Acne, hirsutism, and seborrhea are also DHT-related conditions, in addition, antiandrogens like cyproterone acetate, spironolactone, and bicalutamide, as well as estrogens like ethinylestradiol, may also be used to treat these conditions. It was first described in a paper by scientists from Syntex and its primary clinical applications include treatment of osteoporosis and anaemia, as well as stimulating muscle growth in malnourished or underdeveloped patients.

    The drug was approved for use by the FDA. Later, non-steroidal drugs such as epoetin alfa were developed and proven to be effective as a treatment for anaemia. The drug remained available despite this and eventually found a new use in treating HIV wasting syndrome, presented most commonly as a 50 mg tablet, oxymetholone is one of the strongest androgenic steroids available.

    Similarly, there is a risk of side effects, despite very low binding affinity with the androgen receptor, oxymetholone is highly effective in promoting extensive gains in body mass, mostly by greatly improving protein synthesis. For this reason, it is used by bodybuilders and athletes. In women, side effects include acne, changes in menstrual periods, deepened voice, hair growth on the chin or chest, male pattern baldness, enlarged clitoris.

    Estanozolol — Stanozolol, commonly sold under the name Winstrol and Winstrol Depot, is a synthetic anabolic steroid derived from dihydrotestosterone. It was developed by American pharmaceutical company Winthrop Laboratories in , unlike most injectable anabolic steroids, stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form.

    It is because of this that stanozolol is also sold in tablet form, Stanozolol has been used in both animal and human patients for a number of conditions.

    In humans, it has demonstrated to be successful in treating anaemia. Veterinarians may prescribe the drug to improve growth, red blood cell production, increase bone density.

    Additionally, stanozolol has been used in US horse racing, Stanozolol is subject to non-medically supervised off-label use by some athletes for its anabolic properties frequently presenting with concomitant reduction of body fat.

    Stanozolol is a derivative of dihydrotestosterone and thus not aromatized to oestrogens via the aromatase class of enzymes. Stanozolol is used by athletes and bodybuilders to lose fat while retaining lean body mass, Stanozolol is subject to extensive hepatic biotransformation by a variety of enzymatic pathways.

    The primary metabolites are unique to stanozolol and are detectable in the urine for up to 10 days after a single 5—10 mg oral dose, methods for detection in urine specimens usually involve gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry.

    In , Stanozolol was brought to market in the US by Winthrop under the tradename Winstrol, the FDA implemented its Drug Efficacy Study Implementation program to study and regulate drugs, including stanozolol, that had been introduced prior to the amendment. In June the FDA announced its conclusions on the effectiveness of certain anabolic steroid drugs, including stanozolol, anabolic steroids are without value as primary therapy but may be of value as adjunctive therapy.

    Equal or greater consideration should be given to diet, calcium balance, physiotherapy, and gave Sterling a timeline to submit further data for other indications it wanted for the drug. Sterling submitted data to the FDA intended to support the effectiveness of Winstrol for postmenopausal osteoporosis and aplastic anemia in December,, the FDAs Endocrinologic and Metabolic Drugs Advisory Committee considered the data submitted for osteoporosis in two meetings held and the data for aplastic anemia in Even with no drug in production, Sanofi sold the business to Ovation Pharmaceuticals in At that time, the drug had not been discontinued and was considered a treatment for hereditary angioedema and it is used as a performance-enhancing drug in race horses.

    Enantato de metenolona — Metenolone enanthate, or methenolone enanthate, is a dihydrotestosterone -based anabolic-androgenic steroid. It is a derivative of metenolone sold commonly under the brand name Primobolan Depot. When it interacts with the enzyme it does not form any estrogens. It is used by people who are susceptible to estrogenic side effects. Metenolone, in form of enanthate and acetate, is available as an injection or as an oral formulation, the injection is regarded as having a higher bioavailability.

    It is an ester which is quite long-acting. Because it by-passes hepatic breakdown on the first pass, it also has a survival rate. The tablets are in a short-lived acetate form, metenolone is not alpha-alkylated, but 1-methylated for oral bioavailability.

    This reduces the stress on the liver, but also the availability, in doses of mg per week or less blood pressure is rarely altered. Metenolone enanthate can be suppressive of the hypothalamic-pituitary-gonadal axis, in February , Sports Illustrated reported that Alex Rodriguez tested positive for two anabolic steroids, testosterone and metenolone enanthate, while playing for the Texas Rangers in He claims to have purchased them over the counter, in the Dominican Republic, however, boli, as he referred to it, is an illegal substance in the Dominican Republic.

    He said he did not know the name of the substance he was using. Metenolone enanthate, which has no approved prescriptive use in the United States of America, is the same steroid to which Barry Bonds allegedly tested positive in and , a weak steroid on its own, it is generally used in conjunction with other steroids. The drug is generally preferred in injected rather than oral form due to its cost. Nandrolona — Nandrolone, also known as nortestosterone or norandrostenolone, is a synthetic anabolic-androgenic steroid derived from testosterone.

    The positive effects of the drug include muscle growth, appetite stimulation and increased red cell production. Erectile dysfunction is attributed to the action of DHN in the penis since dihydrotestosterone is a known sexual modulator. In addition to its activity, unlike many other AAS.

    The progestogenic activity of nandrolone may serve to augment its antigonadotropic effects, Nandrolone has a very high ratio of anabolic to androgenic action. In fact, nandrolone-like AAS like nandrolone itself and trenbolone are said to have among the highest ratio of anabolic to androgenic effect of all AAS. It is the demethylated analogue of testosterone, and for reason, is also known as nortestosterone. A large number of nandrolone esters have been marketed and used clinically, the most commonly used esters are nandrolone decanoate and nandrolone phenylpropionate.

    Nandrolone is the parent compound of a group of AAS. They are subdivided into two groups, the estranes and the gonanes, initial reaction constituents of 1, 4-dimetalation of the most electron deficient positions of the aromatic ring—in the case of an estrogen, the 1 and 4-positions. Treatment of this product with weak acid, oxalic acid for e. Trembolona — It is used in veterinary medicine in livestock to increase muscle growth and appetite.

    Trenbolone is used in the form of ester prodrugs, including trenbolone acetate, although it is not available as a prescription medication for humans, trenbolone enanthate is sometimes sold under the nickname Trenabol. Trenbolone improves muscle mass, feed efficiency, and mineral absorption in cattle and it has both anabolic and androgenic effects.

    SciELO - Scientific Electronic Library Online

    que son los esteroides anabolizantes androgenicos

    Esteroides y Anabolizantes by Natalia Reyes on Prezi

    que son los esteroides anabolizantes androgenicos

    Anabolizante androgénico esteroideo

    que son los esteroides anabolizantes androgenicos