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Unlike most oral steroids, which are Class II steroids giving most of their anabolic effect by means other than the androgen receptor AR , it seems that oxandrolone probably does have good binding to the AR, and is therefore a Class I steroid, while having little other effect. By itself it is considered to be a weak anabolic. Partly this is due to its apparent lack of non-AR-mediated activity. The other part of the reason for this is that bodybuilders make unfortunate and unreasonable comparisons when judging anabolic steroids.
If say 8 tablets per day does little, then the drug is pronounced useless or weak by the user. Few anabolic steroids give dramatic results at that dose. Per milligram the potency is reasonable, but each individual tablet is weak because the dosage is small. Because of its high price, very few bodybuilders have taken large doses of oxandrolone.
There is a single case in the medical literature Forbes et al. This is of uncertain credibility because unless urinalysis was done to verify that no other steroids were taken, there is no way to be certain that the athlete did not actually take more drugs than he reported.
In any case, at current prices, only the quite wealthy could afford such a dose. Oxandrolone does not aromatize or convert to DHT, and has a longer half life than Dianabol - 8 hours vs. Thus, a moderate dose taken in the morning is largely out of the system by night, yet supplies reasonable levels of androgen during the day and early evening.
Oxandrolone shares the liver toxicity problems common to alkylated steroids. Primobolan, I believe, should be considered a superior compound, offering the same activity at usually a lower price and without the alkylated-toxicity issue. Common uses and directions for Anavar, oxandrolone Oxandrolone has often been used as a growth-promoting agent in the therapy of boys with growth delays in adolescence.
Oxandrolone is also used in treating girls affected with Turner's syndrome, another growth-delay ailment. In obese individuals, oral oxandrolone has been shown to decrease subcutaneous abdominal fat more than Testosterone enanthate or weight loss alone, and it also tended to produce favorable changes in visceral fat.
Athletes like oxandrolone for three reasons. First, oxandrolone causes a strong strength gain by stimulating the phosphocreatine synthesis in the muscle cell without depositing water in the joints and the muscles. Secondly, oxandrolone is one of the very few steroids that does not aromatize into estrogen, at any dosage, which has various advantages for the athlete. The third reason for the popularity of Anavar is that oxandrolone does not influence the body's own testosterone production.
A suitable dosage of Anavar for a male athlete is 0. Women should not take more than about half of that dosage, though. Anavar is normally taken two to three times daily after meals thus assuring an optimal absorption of the oxandrolone. Oxandrolone can give gastrointestinal problems ranging from a sensation of stomach fullness to appetite suppression, nausea, and diarrhea. This special feature of Anavar can be explained by the fact that the oxandrolone is not converted into estrogen. Oxandrolone causes very light virilization symptoms, if at all.
This characteristic makes Anavar a favored remedy for female athletes since, at a daily dose of mg. Directions Anavar, brand name Bonavar, as a tablet, containing 2. Anavar should be taken two to three times daily after meals thus assuring an optimal absorption of the oxandrolone. Common dosage is tablets in men and tablets in women. The rule of thumb to take 0.
Anavar can be combined with almost any other steroid such as Winstrol , Deca durabolin, Dianabol , or Anadrol. If you miss a dose, take it as soon as remembered if it is within an hour or so.
If you do not remember until later, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up. Precautions Women should not take more than 15 mg. Since oxandrolone is only slightly toxic and usually shows few side effects, several athletes use it over a prolonged period of time.
However Anavar should not be taken for several consecutive months, since, as with almost all oral steroids it is 1 7-alpha alkylated and thus liver toxic. The symptoms can be reduced by taking the tablets one-two hours after the meals. Oxandrolone has negative effects on blood lipids.
In females, dosages above 15 mg. If you notice other effects not listed above, contact your doctor. Overdose If overdose of anavar is suspected, contact your local poison control center or emergency room immediately. Keep oxandrolone in a tightly closed container and out of reach of children. Store oxandrolone at room temperature and away from excess heat and moisture not in the bathroom.
The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, or other healthcare professional. It should not be construed to indicate that use of oxandrolone is safe, appropriate, or effective for you. Consult your healthcare professional before using anavar. Each product contain secret verification code that you can find under the scratch area of the box. This code contains 10 alphanumeric characters. Each code is unique and can not be replicated by the system.
Write your code on the box below. If the product you purchased has been made by us you will receive a message - your code is valid. If you receive a message your code is invalid, it means that you have been subject to fraud and have purchased a product that not contains our values and ingredients. Anavar was the old U. It was designed as an extremely mild anabolic, one that could even be safely used as a growth stimulant in children.
One immediately thinks of the standard worry, "steroids will stunt growth". But it is actually the excess estrogen produced by most steroids that is the culprit, just as it is the reason why women stop growing sooner and have a shorter average stature than men. Oxandrolone will not aromatize, and therefore the anabolic effect of the compound can actually promote linear growth. Women usually tolerate this drug well at low doses, and at one time it was prescribed for the treatment of osteoporosis.
As the opinions surrounding steroids began to change in the 's, prescriptions for oxandrolone began to drop. Lagging sales probably led Searle to discontinue manufacture in , and it had vanished from U. Oxandrolone tablets are again available inside the U. Anavar is a mild anabolic with low androgenic activity. Its reduced androgenic activity is due to the fact that it is a derivative of dihydrotestosterone DHT. Although one might think that this would make it a more androgenic steroid, it in fact creates a steroid that is less androgenic because it is already "5-alpha reduced".
It is a simple matter of where a steroid is capable of being potentiated in the body, and with oxandrolone we do not have the same potential as testosterone, which is several times more active in androgen responsive tissues compared to muscle tissue due to its conversion to DHT.
It essence oxandrolone has a balanced level of potency in both muscle and androgenic target tissues such as the scalp, skin and prostate. This is a similar situation as is noted with Primobolan and Winstrol, which are also derived from dihydrotestosterone yet not known to be very androgenic substances. This steroid works well for the promotion of strength and duality muscle mass gains, although it's mild nature makes it less than ideal for bulking purposes.
Among bodybuilders it is most commonly used during cutting phases of training when water retention is a concern. The standard dosage for men is in the range of mg per day, a level that should produce noticeable results. It can be further combined with anabolics like Primobolan and Winstrol to elicit a harder, more defined look without added water retention.
Such combinations are very popular and can dramatically enhance the show physique. One can also add strong non-aromatizing androgens like Halotestin, Proviron or trenbolone.
In this case the androgen really helps to harden up the muscles, while at the same time making conditions more favorable for fat reduction. Some athletes do choose to incorporate oxandrolone into bulking stacks, but usually with standard bulking drugs like testosterone or Dianabol. The usual goal in this instance is an additional gain of strength, as well as more quality look to the androgen bulk. Women who fear the masculinizing effects of many steroids would be quite comfortable using this drug, as this is very rarely seen with low doses.
Here a daily dosage of 5mg should illicit considerable growth without the noticeable androgenic side effects of other drugs. Eager females may wish to addition mild anabolics like Winstrol, Primobolan or Durabolin. When combined with such anabolics, the user should notice faster, more pronounced muscle-building effects, but may also increase the likelihood of androgenic buildup.
Studies using low dosages of this compound note minimal interferences with natural testosterone production. This has a lot to do with the fact that it does not convert to estrogen, which we know has an extremely profound effect on endogenous hormone production. Without estrogen to trigger negative feedback, we seem to note a higher threshold before inhibition is noted. Anavar is also a 17alpha alkylated oral steroid, carrying an alteration that will put stress on the liver. It is important to point out however that dispite this alteration oxandrolone is generally very well tolerated.
While liver enzyme tests will occasionally show elevated values, actual damage due to this steroid is not usually a problem. Bio-Technology General states that oxandrolone is not as extensively metabolized by the liver as other l7aa orals are; evidenced by the fact that nearly a third of the compound is still intact when excreted in the urine. This may have to do with the understood milder nature of this agent compared to other l7aa orals in terms of hepatotoxicity.
One study comparing the effects of oxandrolone to other agents including as methyltestosterone, norethandrolone, fluoxymesterone and methAndriol clearly supports this notion.
Here it was demonstrated that oxandrolone causes the lowest sulfobromophthalein BSP; a marker of liver stress retention among all the alkylated orals tested. With such findings, combined with the fact that athletes rarely report trouble with this drug, most feel comfortable believing it to be much safer to use during longer cycles than most of other orals with this distinction. Although this may very well be true, the chance of liver damage still cannot be excluded, especially with hogher dosages.
At one time oxandrolone was also looked at as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed it to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients, which initially this was thought to signify potential for this drug as a hypo-lipid lipid lowering agent.
With further investigation we find however that while use of this drug can be linked to a lowering of total cholesterol values, it is such that a redistribution in the ratio of good HDL to bad LDL cholesterol occurs, usually moving values in an unfavorable direction.